Health
GLP-1 Drugs Are Becoming More Than Weight Loss Medicine
Tirzepatide just earned an approval that has nothing to do with the scale. Here is what SELECT, FLOW and the new sleep apnea data show.
Jan 8, 2025
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25 stories for“weight loss trials”
Nutrition
Low-Carb vs Low-Fat: What Decades of Trials Converged On
The biggest head-to-head diet trial ever run found near-identical weight loss. The real variable turned out to be the person, not the macro.
Nov 18, 2024
Health
Mounjaro and Zepbound: The Case for Two Hormones at Once
Tirzepatide just beat semaglutide head to head in a major trial. Here is what SURMOUNT and SURPASS data actually shows about hitting two receptors.
Dec 9, 2024
Health
What Actually Happens When You Stop Taking a GLP-1
Trial data on stopping semaglutide shows most of the lost weight comes back within a year. Here is what the STEP 1 extension found.
May 15, 2024
Nutrition
Intermittent Fasting: What the Trials Actually Show
A major Cochrane review of nearly 2,000 people found intermittent fasting barely beats ordinary dieting. Here is what the data really supports.
Mar 10, 2026
Health
Retatrutide's Phase 3 Run Is Nearly Complete. The Numbers Are the Largest Yet
TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026
Health
Berberine and the 'Nature's Ozempic' Claim: What Evidence Shows
Berberine lowers cholesterol and blood sugar in small trials, but comparing it to semaglutide misreads both the data and the biology.
Feb 14, 2024
Health
Intermittent Fasting Works About as Well as Eating Less, Because in the Trials That Is What It Turned Out to Be
Three randomised trials put time-restricted eating against ordinary calorie control or against nothing. The eating window on its own did little. Combined with eating less, it did what eating less does. What that means for anyone considering it.
Sep 6, 2026
Health
Retatrutide: The Triple Agonist Still Proving Itself
Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026
Health
Ozempic and Wegovy: What the Trials Actually Showed
Semaglutide now has a heart disease approval too. Here is what the STEP and SELECT trial data really says, and what it does not.
Mar 13, 2024
Health
Nearly Half the People in a Trial Put Their Type 2 Diabetes Into Remission. The Follow-Up Is the Interesting Part
DiRECT reported 46 per cent remission at one year and 36 per cent at two. Among those who lost more than ten kilograms, three quarters were in remission. At five years, the picture is more sobering and more useful.
Aug 12, 2026
Nutrition
Why Fast Weight Loss Is Not Evidence That a Diet Is Right
Every restrictive plan produces results in the first month, including plans that contradict each other completely. That is a fact about restriction, not about the theory attached to it.
Jun 30, 2026
Health
One Receptor, Two, or Three: Comparing Semaglutide, Tirzepatide and Retatrutide
Ozempic, Mounjaro and the drug that has not arrived yet are not three versions of the same thing. They hit different receptors, produce different results, and suit different people.
Aug 11, 2026
Health
Muscle Loss on GLP-1s: What the Evidence Really Shows
New body composition data compares lean mass loss on tirzepatide and semaglutide. Here is what is measured, and what remains unclear.
Jun 15, 2026
Health
What Short Sleep Actually Does to Metabolic Health, According to Research
Trials now show insufficient sleep impairs insulin sensitivity directly, independent of weight gain, reshaping how doctors talk about diabetes risk.
Nov 2, 2024
Health
The GLP-1 Era: How Weight-Loss Drugs Changed Us
Semaglutide and tirzepatide went from diabetes treatment to celebrity shortcut to a genuine health story. What happens when one drug becomes a cultural moment.
Apr 20, 2024
Lifestyle
More Companies Ordered People Back to the Office This Year, and the Best Studies Still Do Not Support It
A controlled trial found two days at home produced no measurable productivity loss and cut resignations by a third. A study of large listed firms found return to office mandates did not improve company value. Mandates increased anyway.
Aug 22, 2026
Health
Prediabetes Is Not a Disease. It Is a Warning With Unusually Good Evidence Behind It
The label is contested, the thresholds differ between guidelines, and most people who have it never progress. It is also the one point in this whole condition where a trial showed you can change the outcome by more than half.
Jul 10, 2026
Health
Retatrutide's Third Receptor Is the Hormone That Raises Blood Sugar. Adding It On Purpose Is the Whole Idea
Semaglutide hits one receptor and tirzepatide hits two. The third one retatrutide adds is glucagon, which does the opposite of what a diabetes drug is supposed to do. It is also where the liver results and the safety questions both come from.
Aug 20, 2026
Health
Retatrutide Is Not Approved in Any Country. It Is Also for Sale in Most of Them
Lilly does not expect to file for approval until the first quarter of 2027. Search the drug's name today and you can have a vial by the weekend. The gap between those two facts is where the harm happens.
Aug 20, 2026
Health
Two Camps, One Diet: Why the Argument Never Converged
Doctors and followers spent a year disagreeing about nizam al-tayyibat without ever contradicting each other, because they were not answering the same question.
Jul 24, 2026
Health
Muscle Pulls Glucose Out of Your Blood Without Asking Insulin's Permission
Contracting muscle opens a separate doorway for glucose that does not require insulin at all. It explains why a ten minute walk after dinner works, why lifting weights matters more than it is given credit for, and why a hard sprint can send the number up.
Aug 9, 2026
Nutrition
The Low FODMAP Diet Is a Diagnostic Tool, Not a Way of Eating
It has strong evidence behind it for irritable bowel syndrome, and it is routinely misused. The elimination phase is meant to last weeks, and the part people skip is the part that matters.
Aug 7, 2026
Nutrition
Mediterranean Diet Keeps Winning: What Research Says
The Mediterranean diet isn't trendy, it's proven. New 2025 research shows it cuts diabetes risk by a third when combined with lifestyle changes.
Feb 10, 2025
Nutrition
Coeliac, Wheat Allergy or Gluten Sensitivity: They Are Not the Same Thing
Three different conditions get flattened into one phrase. One is autoimmune, one is an allergy and one is a diagnosis of exclusion, and the testing order matters more than most people realise.
Aug 8, 2026
