Muscle Loss on GLP-1s: What the Evidence Really Shows
New body composition data compares lean mass loss on tirzepatide and semaglutide. Here is what is measured, and what remains unclear.
Jun 15, 2026

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13 stories for“muscle mass aging”
New body composition data compares lean mass loss on tirzepatide and semaglutide. Here is what is measured, and what remains unclear.
Jun 15, 2026

New mortality data pinpoints how much weekly strength training lowers death risk, and shows more is not always better.
Apr 10, 2025

Decades of trials back creatine for muscle and strength, and newer research is testing brain benefits, but the hype has outrun some of the data.
Aug 19, 2024

Contracting muscle opens a separate doorway for glucose that does not require insulin at all. It explains why a ten minute walk after dinner works, why lifting weights matters more than it is given credit for, and why a hard sprint can send the number up.
Aug 9, 2026

In 1,900 American adults, waist circumference on its own matched a new multi measurement framework against a proper body fat scan. BMI alone missed a substantial number of people who met the body fat criteria for obesity.
Sep 1, 2026

Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026

Ozempic, Mounjaro and the drug that has not arrived yet are not three versions of the same thing. They hit different receptors, produce different results, and suit different people.
Aug 11, 2026

TRIUMPH-2 and TRIUMPH-3 read out in July, following TRIUMPH-1 in May. Across the programme the triple agonist has produced weight loss in a range no approved obesity drug has reached, with a filing due in early 2027.
Aug 11, 2026

Semaglutide hits one receptor and tirzepatide hits two. The third one retatrutide adds is glucagon, which does the opposite of what a diabetes drug is supposed to do. It is also where the liver results and the safety questions both come from.
Aug 20, 2026

Semaglutide now has a heart disease approval too. Here is what the STEP and SELECT trial data really says, and what it does not.
Mar 13, 2024

Three randomised trials put time-restricted eating against ordinary calorie control or against nothing. The eating window on its own did little. Combined with eating less, it did what eating less does. What that means for anyone considering it.
Sep 6, 2026
