Health
Metformin as an Anti-Aging Drug: The Claims Versus the Trial Data
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024
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6 stories for“longevity drugs”
Health
An AI-Designed Lung Drug Made Six Ageing Clocks Run Backwards in a Small Trial. That Is Not the Same as Reversing Ageing
Rentosertib was built to treat pulmonary fibrosis. In 42 patients, blood proteins read by six independent clocks came out three to four years younger after a month. Independent doctors say a younger score is not a younger person.
Sep 15, 2026
Health
Strength Training for Longevity: Muscle as an Organ of Healthspan
New mortality data pinpoints how much weekly strength training lowers death risk, and shows more is not always better.
Apr 10, 2025
Health
An FDA Panel Just Backed Compounded BPC-157. That Is Not the Same as Approval
On 23 and 24 July, an FDA advisory committee looked at seven peptides and recommended that pharmacies be allowed to compound several of them. The vote is not binding, and the evidence gap has not moved.
Aug 11, 2026
Health
Intermittent Fasting Works About as Well as Eating Less, Because in the Trials That Is What It Turned Out to Be
Three randomised trials put time-restricted eating against ordinary calorie control or against nothing. The eating window on its own did little. Combined with eating less, it did what eating less does. What that means for anyone considering it.
Sep 6, 2026
Health
Something Has Been Crossing Into the Ageing Human Brain That Was Not Supposed to Get In
Stanford researchers borrowed the trick a consumer ancestry test uses and found immune cells migrating out of the blood and into the human brain from middle age onwards. Mice do not do it. Nor did the primates tested alongside them.
Aug 25, 2026
