Metformin as an Anti-Aging Drug: The Claims Versus the Trial Data
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024

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60 stories for“claims”
Biohackers take metformin to slow aging, but the trial designed to actually prove that, TAME, still has not finished enrolling.
May 6, 2024

Yogic breathing is unusual among wellness practices in having a measurable, replicated physiological effect. The size of it is modest, the mechanism is well understood, and a few of the more dramatic techniques carry real risk.
Sep 4, 2026

Berberine lowers cholesterol and blood sugar in small trials, but comparing it to semaglutide misreads both the data and the biology.
Feb 14, 2024

Telling people to eat differently is one thing. Telling type 1 diabetics they can stop injecting is another, and it is the claim that brought regulators down on nizam al-tayyibat.
May 25, 2026

Three thousand Dutch adults who ended their showers cold took fewer sick days. A 2025 review of eleven trials found stress fell twelve hours after a plunge and inflammation rose. What is known, what is marketing, and why the first minute can kill.
Sep 6, 2026

A guided practice of lying still while systematically moving attention around the body. It has accumulated a real randomised trial literature for sleep, stress and anxiety, and a rebranded version has attracted claims that literature does not support.
Sep 4, 2026

Decades of trials back creatine for muscle and strength, and newer research is testing brain benefits, but the hype has outrun some of the data.
Aug 19, 2024

Insulin is a peptide. So is Ozempic. So is the unlabelled vial someone is selling on Telegram. The word describes a chemical class, not a level of evidence, and that gap is where the market lives.
Aug 11, 2026

VO2 max strongly predicts longevity, but the evidence that slow, low-intensity Zone 2 training is the best way to raise it is weaker than the trend suggests.
Jan 15, 2025

Two Ayurvedic oral practices have gone mainstream on very different evidence bases. Neither replaces a toothbrush, and one of them has a Cochrane review that found two trials and forty people.
Sep 4, 2026

A UAE medical report found a natural death from sudden cardiac arrest. Egypt then exhumed the body for a second examination. Both of those facts are true, and neither cancels the other.
May 17, 2026

Semaglutide now has a heart disease approval too. Here is what the STEP and SELECT trial data really says, and what it does not.
Mar 13, 2024

Doctors and followers spent a year disagreeing about nizam al-tayyibat without ever contradicting each other, because they were not answering the same question.
Jul 24, 2026

Retatrutide just posted phase 3 weight loss data hitting three hormone receptors at once. Here is what is confirmed and what remains unproven.
May 27, 2026

A new WHO discussion brings cognition and mental health into menopause care, where sleep, mood, symptoms and individual medical history all matter.
Jul 31, 2026

Peptide is a chemical category, not a claim. The two versions most people actually buy are the ones with the least regulation and, oddly, the best safety record. Here is what the trials support and what physics gets in the way of.
Aug 20, 2026
